Eric Greene’s lab founded at San Francisco State

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The Greene Lab at San Francisco State University will be opening in the coming school year. The lab’s goal is to understand how protein motions contribute to enzyme catalysis, regulation, and protein turnover for large enzyme complexes by combining cryoEM with enzymology techniques.

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New website

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Lauching a new website for the Greene Lab

Large language models generate functional protein sequences across diverse families

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We recently published “Large language models generate functional protein sequences across diverse families” in Nature Biotechnology.

Site-specific ubiquitination affects protein energetics and proteasomal degradation

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We recently published “Site-specific ubiquitination affects protein energetics and proteasomal degradation” in Nature Chemical Biology.

Specific lid-base contacts in the 26S proteasome control the conformational switching required for substrate degradation

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We recently published “Specific lid-base contacts in the 26S proteasome control the conformational switching required for substrate degradation” in eLife.

Eric Greene

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New website

Large language models generate functional protein sequences across diverse families

Site-specific ubiquitination affects protein energetics and proteasomal degradation

Specific lid-base contacts in the 26S proteasome control the conformational switching required for substrate degradation