Large language models generate functional protein sequences across diverse families

Ali Madani, Ben Krause, Eric R. Greene, Subu Subramanian, Benjamin P. Mohr, James M. Holton, Jose Luis Olmos Jr., Caiming Xiong, Zachary Z. Sun, Richard Socher, James S. Fraser, and Nikhil Naik

Published in Nature Biotechnology 41, 1099–1106 (2023).

PDB: 7RGR

Site-specific ubiquitination affects protein energetics and proteasomal degradation

Emma C. Carroll, Eric R. Greene, Andreas Martin, and Susan Marqusee

Published in Nature Chemical Biology 16, 866-875 (2020).

Specific lid-base contacts in the 26S proteasome control the conformational switching required for substrate degradation

Eric R. Greene, Ellen A. Goodall, Andres H. de la Peña, Mary E. Matyskiela, Gabriel C. Lander, and Andreas Martin

Published in eLife 2019;8:e49806.

Understanding the 26S proteasome molecular machine from a structural and conformational dynamics perspective

Eric R. Greene, Ken C. Dong, and Andreas Martin

Published in Current Opinion in Structural Biology 2020, 61:33-41.

Ubiquitination modulates a protein energy landscape site-specifically with consequences for proteasomal degradation

Emma C. Carroll, Eric R. Greene, Andreas Martin, and Susan Marqusee

Published in bioRxiv .

Structure and Function of the 26S Proteasome

Jared A.M. Bard, Ellen A. Goodall, Eric R. Greene, Erik Jonsson, Ken C. Dong, and Andreas Martin

Published in Annual Review of Biochemistry 2018. 87:697-724.

Glycosylation of Cellulase: Engineering Better Enzymes for Biofuels

Eric R. Greene, Michael E. Himmel, Gregg T. Beckham, and Zhongping Tan

Published in Advances in Carbohydrate Chemistry and Biochemistry 72 (2015) 63-112.

Molecular-scale features that govern the effects of O-glycosylation on a carbohydrate-binding module

Xiaoyang Guan, Patrick K. Chaffey, Chen Zeng, Eric R. Greene, Liqun Chen, Matthew R. Drake, Claire Chen, Ari Groobman, Michael G. Resch, Michael E. Himmel, Gregg T. Beckham, and Zhongping Tan

Published in Chemical Science 2015, 6, 7185-7189.

Whole genome comparison of a large collection of mycobacteriophages reveals a continuum of phage genetic diversity

Welkin H Pope, Charles A. Bowman, Daniel A. Russell, Deborah Jacobs-Sera, David J. Asai, Steven G. Cresawn, William R. Jacobs, Jr., Roger W. Hendrix, Jeffrey G. Lawrence, Graham F. Hatfull, Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science, Phage Hunters Integrating Research and Education, and Mycobacterial Genetics Course

Published in eLife 2015;4:e06416.

Specificity of O-glycosylation in enhancing the stability and cellulose binding affinity of Family 1 carbohydrate-binding modules

Liqun Chen, Matthew R. Drake, Michael G. Resch, Eric R. Greene, Michael E. Himmel, Patrick K. Chaffey, Gregg T. Beckham, and Zhongping Tan

Published in PNAS 111 (21) 7612-7617.