Greene Lab @ SFSU

Eric Greene

Assistant Professor Department Chemistry and Biochemistry

The Greene Lab’s goal is to understand how protein motions contribute to enzyme catalysis, regulation, and protein turnover for large enzyme complexes by combining cryoEM with enzymology techniques. GS mechanism

Site-specific ubiquitination affects protein energetics and proteasomal degradation

less than 1 minute read

We recently published “Site-specific ubiquitination affects protein energetics and proteasomal degradation” in Nature Chemical Biology.

Specific lid-base contacts in the 26S proteasome control the conformational switching required for substrate degradation

less than 1 minute read

We recently published “Specific lid-base contacts in the 26S proteasome control the conformational switching required for substrate degradation” in eLife.

Understanding the 26S proteasome molecular machine from a structural and conformational dynamics perspective

less than 1 minute read

We recently published “Understanding the 26S proteasome molecular machine from a structural and conformational dynamics perspective” in Current Opinion in St...

Ubiquitination modulates a protein energy landscape site-specifically with consequences for proteasomal degradation

less than 1 minute read

We recently published “Ubiquitination modulates a protein energy landscape site-specifically with consequences for proteasomal degradation” in bioRxiv.

Structure and Function of the 26S Proteasome

less than 1 minute read

We recently published “Structure and Function of the 26S Proteasome” in Annual Review of Biochemistry.

Eric Greene

Recent Posts

Site-specific ubiquitination affects protein energetics and proteasomal degradation

Specific lid-base contacts in the 26S proteasome control the conformational switching required for substrate degradation

Understanding the 26S proteasome molecular machine from a structural and conformational dynamics perspective

Ubiquitination modulates a protein energy landscape site-specifically with consequences for proteasomal degradation

Structure and Function of the 26S Proteasome